null

SMILES: CC(C)Oc1cc(NS(=O)(=O)C2CC2)ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1

InChI Key: InChIKey=HIQBGIUTDZYFOT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 451757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 4 (Homo sapiens (Human))	BDBM451757 (N-(4-(6-amino-5-(1-oxo- 1,2,3,4-tetrahydroisoquino...) Show SMILES CC(C)Oc1cc(NS(=O)(=O)C2CC2)ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C26H28N4O4S/c1-15(2)34-24-13-19(30-35(32,33)20-5-6-20)4-8-21(24)18-12-23(25(27)29-14-18)16-3-7-22-17(11-16)9-10-28-26(22)31/h3-4,7-8,11-15,20,30H,5-6,9-10H2,1-2H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 26 (Homo sapiens (Human))	BDBM451757 (N-(4-(6-amino-5-(1-oxo- 1,2,3,4-tetrahydroisoquino...) Show SMILES CC(C)Oc1cc(NS(=O)(=O)C2CC2)ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C26H28N4O4S/c1-15(2)34-24-13-19(30-35(32,33)20-5-6-20)4-8-21(24)18-12-23(25(27)29-14-18)16-3-7-22-17(11-16)9-10-28-26(22)31/h3-4,7-8,11-15,20,30H,5-6,9-10H2,1-2H3,(H2,27,29)(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 24 (Homo sapiens (Human))	BDBM451757 (N-(4-(6-amino-5-(1-oxo- 1,2,3,4-tetrahydroisoquino...) Show SMILES CC(C)Oc1cc(NS(=O)(=O)C2CC2)ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C26H28N4O4S/c1-15(2)34-24-13-19(30-35(32,33)20-5-6-20)4-8-21(24)18-12-23(25(27)29-14-18)16-3-7-22-17(11-16)9-10-28-26(22)31/h3-4,7-8,11-15,20,30H,5-6,9-10H2,1-2H3,(H2,27,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM451757 (N-(4-(6-amino-5-(1-oxo- 1,2,3,4-tetrahydroisoquino...) Show SMILES CC(C)Oc1cc(NS(=O)(=O)C2CC2)ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C26H28N4O4S/c1-15(2)34-24-13-19(30-35(32,33)20-5-6-20)4-8-21(24)18-12-23(25(27)29-14-18)16-3-7-22-17(11-16)9-10-28-26(22)31/h3-4,7-8,11-15,20,30H,5-6,9-10H2,1-2H3,(H2,27,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair