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SMILES: COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1

InChI Key: InChIKey=MPHGPIVRFONGMX-ODLFYWEKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 454326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxidized low-density lipoprotein receptor 1 (Bovine)	BDBM454326 (US10717734, Compound 2) Show SMILES COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H28FN3O4S/c1-16-21(13-17-5-8-20(9-6-17)33(30,31)27(2)3)22-14-18(24(29)32-4)7-10-23(22)28(16)15-19(25)11-12-26/h5-11,14H,12-13,15,26H2,1-4H3/b19-11-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM454326 (US10717734, Compound 2) Show SMILES COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H28FN3O4S/c1-16-21(13-17-5-8-20(9-6-17)33(30,31)27(2)3)22-14-18(24(29)32-4)7-10-23(22)28(16)15-19(25)11-12-26/h5-11,14H,12-13,15,26H2,1-4H3/b19-11-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM454326 (US10717734, Compound 2) Show SMILES COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H28FN3O4S/c1-16-21(13-17-5-8-20(9-6-17)33(30,31)27(2)3)22-14-18(24(29)32-4)7-10-23(22)28(16)15-19(25)11-12-26/h5-11,14H,12-13,15,26H2,1-4H3/b19-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM454326 (US10717734, Compound 2) Show SMILES COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H28FN3O4S/c1-16-21(13-17-5-8-20(9-6-17)33(30,31)27(2)3)22-14-18(24(29)32-4)7-10-23(22)28(16)15-19(25)11-12-26/h5-11,14H,12-13,15,26H2,1-4H3/b19-11-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
					More data for this Ligand-Target Pair