Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Membrane primary amine oxidase' and Ligand = 'BDBM454326'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM454326 (US10717734, Compound 2) Show SMILES COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H28FN3O4S/c1-16-21(13-17-5-8-20(9-6-17)33(30,31)27(2)3)22-14-18(24(29)32-4)7-10-23(22)28(16)15-19(25)11-12-26/h5-11,14H,12-13,15,26H2,1-4H3/b19-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
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