BDBM46664 3-(6-methoxy-1,3-benzothiazol-2-yl)-1,1-dimethyl-thiourea::3-(6-methoxy-1,3-benzothiazol-2-yl)-1,1-dimethylthiourea::MLS-0072968.0001::cid_944467

SMILES: COc1ccc2nc(NC(=S)N(C)C)sc2c1

InChI Key: InChIKey=NRJLSHZZYRBGGG-UHFFFAOYSA-N

Data: 5 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 46664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
eukaryotic translation initiation factor 4 gamma, 1 isoform 4 (Homo sapiens (Human))	BDBM46664 (3-(6-methoxy-1,3-benzothiazol-2-yl)-1,1-dimethyl-t...) Show SMILES COc1ccc2nc(NC(=S)N(C)C)sc2c1 Show InChI InChI=1S/C11H13N3OS2/c1-14(2)11(16)13-10-12-8-5-4-7(15-3)6-9(8)17-10/h4-6H,1-3H3,(H,12,13,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2RN3686
					More data for this Ligand-Target Pair
phosphomannomutase 2 (Homo sapiens (Human))	BDBM46664 (3-(6-methoxy-1,3-benzothiazol-2-yl)-1,1-dimethyl-t...) Show SMILES COc1ccc2nc(NC(=S)N(C)C)sc2c1 Show InChI InChI=1S/C11H13N3OS2/c1-14(2)11(16)13-10-12-8-5-4-7(15-3)6-9(8)17-10/h4-6H,1-3H3,(H,12,13,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CJ8BWC
					More data for this Ligand-Target Pair
DNA dC->dU-editing enzyme APOBEC-3G (Homo sapiens (Human))	BDBM46664 (3-(6-methoxy-1,3-benzothiazol-2-yl)-1,1-dimethyl-t...) Show SMILES COc1ccc2nc(NC(=S)N(C)C)sc2c1 Show InChI InChI=1S/C11H13N3OS2/c1-14(2)11(16)13-10-12-8-5-4-7(15-3)6-9(8)17-10/h4-6H,1-3H3,(H,12,13,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.08E+4	n/a	n/a	n/a	n/a	n/a	25
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2HQ3XD6
					More data for this Ligand-Target Pair
MPI protein (Homo sapiens (Human))	BDBM46664 (3-(6-methoxy-1,3-benzothiazol-2-yl)-1,1-dimethyl-t...) Show SMILES COc1ccc2nc(NC(=S)N(C)C)sc2c1 Show InChI InChI=1S/C11H13N3OS2/c1-14(2)11(16)13-10-12-8-5-4-7(15-3)6-9(8)17-10/h4-6H,1-3H3,(H,12,13,16)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2J964TC
					More data for this Ligand-Target Pair
MPI protein (Homo sapiens (Human))	BDBM46664 (3-(6-methoxy-1,3-benzothiazol-2-yl)-1,1-dimethyl-t...) Show SMILES COc1ccc2nc(NC(=S)N(C)C)sc2c1 Show InChI InChI=1S/C11H13N3OS2/c1-14(2)11(16)13-10-12-8-5-4-7(15-3)6-9(8)17-10/h4-6H,1-3H3,(H,12,13,16)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2C827QV
					More data for this Ligand-Target Pair
Nuclear factor NF-kappa-B (Homo sapiens (Human))	BDBM46664 (3-(6-methoxy-1,3-benzothiazol-2-yl)-1,1-dimethyl-t...) Show SMILES COc1ccc2nc(NC(=S)N(C)C)sc2c1 Show InChI InChI=1S/C11H13N3OS2/c1-14(2)11(16)13-10-12-8-5-4-7(15-3)6-9(8)17-10/h4-6H,1-3H3,(H,12,13,16)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27P8WT7
					More data for this Ligand-Target Pair