BDBM481121 US10906896, Cpd 305

SMILES: CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncc(c3)C3=NN=C(C3)C(=O)N3CCCC3)c2)CC1

InChI Key: InChIKey=NJLUOCLXYPXAHG-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 481121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM481121 (US10906896, Cpd 305) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncc(c3)C3=NN=C(C3)C(=O)N3CCCC3)c2)CC1 |c:39,t:37| Show InChI InChI=1S/C37H40N10O2/c1-25-5-10-30(40-35(48)27-8-6-26(7-9-27)24-46-17-15-45(2)16-18-46)20-32(25)42-37-39-12-11-31(41-37)28-19-29(23-38-22-28)33-21-34(44-43-33)36(49)47-13-3-4-14-47/h5-12,19-20,22-23H,3-4,13-18,21,24H2,1-2H3,(H,40,48)(H,39,41,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Inhibikase Therapeutics, Inc. US Patent					Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...				US Patent US10906896 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM481121 (US10906896, Cpd 305) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncc(c3)C3=NN=C(C3)C(=O)N3CCCC3)c2)CC1 |c:39,t:37| Show InChI InChI=1S/C37H40N10O2/c1-25-5-10-30(40-35(48)27-8-6-26(7-9-27)24-46-17-15-45(2)16-18-46)20-32(25)42-37-39-12-11-31(41-37)28-19-29(23-38-22-28)33-21-34(44-43-33)36(49)47-13-3-4-14-47/h5-12,19-20,22-23H,3-4,13-18,21,24H2,1-2H3,(H,40,48)(H,39,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Inhibikase Therapeutics, Inc. US Patent					Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...				US Patent US10906896 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL2 (Homo sapiens (Human))	BDBM481121 (US10906896, Cpd 305) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncc(c3)C3=NN=C(C3)C(=O)N3CCCC3)c2)CC1 |c:39,t:37| Show InChI InChI=1S/C37H40N10O2/c1-25-5-10-30(40-35(48)27-8-6-26(7-9-27)24-46-17-15-45(2)16-18-46)20-32(25)42-37-39-12-11-31(41-37)28-19-29(23-38-22-28)33-21-34(44-43-33)36(49)47-13-3-4-14-47/h5-12,19-20,22-23H,3-4,13-18,21,24H2,1-2H3,(H,40,48)(H,39,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
Inhibikase Therapeutics, Inc. US Patent					Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...				US Patent US10906896 (2021)
					More data for this Ligand-Target Pair