null
SMILES: CNCCC(Oc1cccc2ncccc12)c1cccs1
InChI Key: InChIKey=ROKYHZXDTGMCJT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human)) | BDBM485704 (N-methyl-3-(quinolin-5- yloxy)-3-(thiophen-2- yl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ESTEVE PHARMACEUTICALS, S.A. US Patent | Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH... | US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human)) | BDBM485704 (N-methyl-3-(quinolin-5- yloxy)-3-(thiophen-2- yl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ESTEVE PHARMACEUTICALS, S.A. US Patent | Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH... | US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens) | BDBM485704 (N-methyl-3-(quinolin-5- yloxy)-3-(thiophen-2- yl)p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ESTEVE PHARMACEUTICALS, S.A. US Patent | Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain... | US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF | |||||||||||
More data for this Ligand-Target Pair |