Compile Data Set for Download or QSAR

Found 404 hits Enz. Inhib. hit(s) with Target = 'Neuroepithelial cell-transforming gene 1 protein'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485748 (3-(3-fluorothiophen-2-yl)- 3-(isoquinolin-5-yloxy)...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1sccc1F Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-11-20-9-5-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485692 (US10941138, Example 1) Show SMILES CNCCC(Oc1cccc2cccnc12)c1cccs1 Show InChI InChI=1S/C17H18N2OS/c1-18-11-9-14(16-8-4-12-21-16)20-15-7-2-5-13-6-3-10-19-17(13)15/h2-8,10,12,14,18H,9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485713 ((S)-3-(isoquinolin-5- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-12-19-10-7-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485770 ((S)-3-(isoquinolin-5- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-11-19-9-5-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485752 ((S)-3-(5-fluorothiophen-2- yl)-3-(isoquinolin-5-yl...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-11-20-10-7-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485784 ((S)-3-(3-Fluorothiophen-2-yl)-3-(isoquinolin-5-ylo...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-11-20-9-5-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485758 (3-(isoquinolin-5-yloxy)-N- methyl-3-(thiophen-3- y...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1ccsc1 Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-11-19-9-5-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485705 (3-(isoquinolin-5-yloxy)- N-methyl-3-(thiophen-2- y...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1cccs1 Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-12-19-10-7-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485743 (3-(5-chlorothiophen-2-yl)- N-methyl-3-(quinolin-5-...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1ccc(Cl)s1 Show InChI InChI=1S/C17H17ClN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485744 (3-(5-fluorothiophen-2-yl)- N-methyl-3-(quinolin-5-...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1ccc(F)s1 Show InChI InChI=1S/C17H17FN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485746 (3-(isoquinolin-5-yloxy)-3- (thiophen-2-yl)propan-1...) Show SMILES NCCC(Oc1cccc2cnccc12)c1cccs1 Show InChI InChI=1S/C16H16N2OS/c17-8-6-15(16-5-2-10-20-16)19-14-4-1-3-12-11-18-9-7-13(12)14/h1-5,7,9-11,15H,6,8,17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485747 (3-(5-fluorothiophen-2-yl)- 3-(isoquinolin-5-yloxy)...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1ccc(F)s1 Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-11-20-10-7-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485749 (3-(3-fluorothiophen-2-yl)- 3-(isoquinolin-8-yloxy)...) Show SMILES CNCCC(Oc1cccc2ccncc12)c1sccc1F Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-5-9-20-11-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485750 (3-(3-fluorothiophen-2-yl)- N-methyl-3-(quinolin-5-...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1sccc1F Show InChI InChI=1S/C17H17FN2OS/c1-19-10-7-16(17-13(18)8-11-22-17)21-15-6-2-5-14-12(15)4-3-9-20-14/h2-6,8-9,11,16,19H,7,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485751 (3-(5-fluorothiophen-2-yl)- 3-(isoquinolin-8-yloxy)...) Show SMILES CNCCC(Oc1cccc2ccncc12)c1ccc(F)s1 Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-7-10-20-11-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485753 ((S)-3-(5-fluorothiophen-2- yl)-N-methyl-3-(quinoli...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485754 ((R)-3-(5-fluorothiophen-2- yl)-3-(isoquinolin-5-yl...) Show SMILES CNCC[C@@H](Oc1cccc2cnccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-11-20-10-7-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485755 ((R)-3-(5-fluorothiophen-2- yl)-N-methyl-3-(quinoli...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485756 (3-(isoquinolin-6-yloxy)-N- methyl-3-(thiophen-2- y...) Show SMILES CNCCC(Oc1ccc2cnccc2c1)c1cccs1 Show InChI InChI=1S/C17H18N2OS/c1-18-8-7-16(17-3-2-10-21-17)20-15-5-4-14-12-19-9-6-13(14)11-15/h2-6,9-12,16,18H,7-8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485727 (3-(isoquinolin-5-yloxy)-N- methyl-3-(pyridin-4- yl...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1ccncc1 Show InChI InChI=1S/C18H19N3O/c1-19-9-8-17(14-5-10-20-11-6-14)22-18-4-2-3-15-13-21-12-7-16(15)18/h2-7,10-13,17,19H,8-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485720 (3-(isoquinolin-5-yloxy)-N- methyl-3-(tetrahydro-2H...) Show SMILES CNCCC(Oc1cccc2cnccc12)C1CCOCC1 Show InChI InChI=1S/C18H24N2O2/c1-19-9-6-17(14-7-11-21-12-8-14)22-18-4-2-3-15-13-20-10-5-16(15)18/h2-5,10,13-14,17,19H,6-9,11-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485719 (3-(isoquinolin-5-yloxy)-N- methyl-3-(pyridin-3- yl...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1cccnc1 Show InChI InChI=1S/C18H19N3O/c1-19-10-8-17(15-5-3-9-20-13-15)22-18-6-2-4-14-12-21-11-7-16(14)18/h2-7,9,11-13,17,19H,8,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485717 ((R)-N-methyl-3-(quinolin- 5-yloxy)-3-(thiophen-2- ...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-11-9-16(17-8-4-12-21-17)20-15-7-2-6-14-13(15)5-3-10-19-14/h2-8,10,12,16,18H,9,11H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485716 ((R)-3-(isoquinolin-5- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@@H](Oc1cccc2cnccc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-12-19-10-7-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485715 ((R)-3-(isoquinolin-8- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@@H](Oc1cccc2ccncc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-7-10-19-12-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485712 ((S)-3-(isoquinolin-8- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@H](Oc1cccc2ccncc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-7-10-19-12-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485796 ((R)-N-methyl-3-(quinolin- 3-yloxy)-3-(thiophen-2- ...) Show SMILES CNCC[C@@H](Oc1cnc2ccccc2c1)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-7-4-10-21-17)20-14-11-13-5-2-3-6-15(13)19-12-14/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485704 (N-methyl-3-(quinolin-5- yloxy)-3-(thiophen-2- yl)p...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1cccs1 Show InChI InChI=1S/C17H18N2OS/c1-18-11-9-16(17-8-4-12-21-17)20-15-7-2-6-14-13(15)5-3-10-19-14/h2-8,10,12,16,18H,9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485788 ((S)-3-(3-Fluorothiophen-2-yl)-3-(isoquinolin-8-ylo...) Show SMILES CNCC[C@H](Oc1cccc2ccncc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-5-9-20-11-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485788 ((S)-3-(3-Fluorothiophen-2-yl)-3-(isoquinolin-8-ylo...) Show SMILES CNCC[C@H](Oc1cccc2ccncc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-5-9-20-11-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485786 ((S)-3-(3-Fluorothiophen-2-yl)-N-methyl-3-(quinolin...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-10-7-16(17-13(18)8-11-22-17)21-15-6-2-5-14-12(15)4-3-9-20-14/h2-6,8-9,11,16,19H,7,10H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485786 ((S)-3-(3-Fluorothiophen-2-yl)-N-methyl-3-(quinolin...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-10-7-16(17-13(18)8-11-22-17)21-15-6-2-5-14-12(15)4-3-9-20-14/h2-6,8-9,11,16,19H,7,10H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485784 ((S)-3-(3-Fluorothiophen-2-yl)-3-(isoquinolin-5-ylo...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-11-20-9-5-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485782 ((S)-3-(5-Fluorothiophen-2-yl)-3-(isoquinolin-8-ylo...) Show SMILES CNCC[C@@H](Oc1cccc2ccncc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-7-10-20-11-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485780 ((S)-3-(5-Chlorothiophen-2-yl)-N-methyl-3-(quinolin...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1ccc(Cl)s1 |r| Show InChI InChI=1S/C17H17ClN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485762 ((R)-3-(isoquinolin-5- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@@H](Oc1cccc2cnccc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-11-19-9-5-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485763 ((R)-3-(isoquinolin-8- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@@H](Oc1cccc2ccncc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-5-9-19-11-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485767 ((S)-N-methyl-3-((1- methylisoquinolin-5- yl)oxy)-3...) Show SMILES CNCC[C@H](Oc1cccc2c(C)nccc12)c1cccs1 |r| Show InChI InChI=1S/C18H20N2OS/c1-13-14-5-3-6-16(15(14)8-11-20-13)21-17(9-10-19-2)18-7-4-12-22-18/h3-8,11-12,17,19H,9-10H2,1-2H3/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485769 ((S)-N-methyl-3-(quinolin- 5-yloxy)-3-(thiophen-3- ...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-10-7-16(13-8-11-21-12-13)20-17-6-2-5-15-14(17)4-3-9-19-15/h2-6,8-9,11-12,16,18H,7,10H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485773 (3-(isoquinolin-5-yloxy)-N- methyl-3-(thiazol-2- yl...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1nccs1 Show InChI InChI=1S/C16H17N3OS/c1-17-7-6-15(16-19-9-10-21-16)20-14-4-2-3-12-11-18-8-5-13(12)14/h2-5,8-11,15,17H,6-7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485776 (3-(isoquinolin-7-yloxy)-N- methyl-3-(thiophen-2- y...) Show SMILES CNCCC(Oc1ccc2ccncc2c1)c1cccs1 Show InChI InChI=1S/C17H18N2OS/c1-18-8-7-16(17-3-2-10-21-17)20-15-5-4-13-6-9-19-12-14(13)11-15/h2-6,9-12,16,18H,7-8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485712 ((S)-3-(isoquinolin-8- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@H](Oc1cccc2ccncc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-7-10-19-12-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485780 ((S)-3-(5-Chlorothiophen-2-yl)-N-methyl-3-(quinolin...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1ccc(Cl)s1 |r| Show InChI InChI=1S/C17H17ClN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485774 (N-methyl-3-(quinolin-5- yloxy)-3-(thiazol-2- yl)pr...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1nccs1 Show InChI InChI=1S/C16H17N3OS/c1-17-9-7-15(16-19-10-11-21-16)20-14-6-2-5-13-12(14)4-3-8-18-13/h2-6,8,10-11,15,17H,7,9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485764 ((R)-N-methyl-3-((1- methylisoquinolin-8- yl)oxy)-3...) Show SMILES CNCC[C@@H](Oc1cccc2ccnc(C)c12)c1cccs1 |r| Show InChI InChI=1S/C18H20N2OS/c1-13-18-14(8-11-20-13)5-3-6-16(18)21-15(9-10-19-2)17-7-4-12-22-17/h3-8,11-12,15,19H,9-10H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485711 ((S)-N-methyl-3-(quinolin- 5-yloxy)-3-(thiophen-2- ...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-11-9-16(17-8-4-12-21-17)20-15-7-2-6-14-13(15)5-3-10-19-14/h2-8,10,12,16,18H,9,11H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485771 ((S)-3-(isoquinolin-8- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@H](Oc1cccc2ccncc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-5-9-19-11-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485760 (3-(isoquinolin-8-yloxy)-N- methyl-3-(thiophen-3- y...) Show SMILES CNCCC(Oc1cccc2ccncc12)c1ccsc1 Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-5-9-19-11-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485732 (3-(isoquinolin-8-yloxy)-N- methyl-3-(4- (trifluoro...) Show SMILES CNCCC(Oc1cccc2ccncc12)c1cc(ccn1)C(F)(F)F Show InChI InChI=1S/C19H18F3N3O/c1-23-8-7-18(16-11-14(6-10-25-16)19(20,21)22)26-17-4-2-3-13-5-9-24-12-15(13)17/h2-6,9-12,18,23H,7-8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM50337829 (1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...) Show SMILES CN(C)CC1(CCCCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H21Cl2N/c1-18(2)11-15(8-4-3-5-9-15)12-6-7-13(16)14(17)10-12/h6-7,10H,3-5,8-9,11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
SUNOVION PHARAMCEUTICALS INC. US Patent					Assay Description Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...				US Patent US10562878 (2020) BindingDB Entry DOI: 10.7270/Q2XP77BX
					More data for this Ligand-Target Pair

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