BDBM48941 4-hydroxy-6-(4-isopropylphenyl)-2-piperidin-1-ylpyrimidine-5-carbonitrile::4-keto-6-p-cumenyl-2-piperidino-1H-pyrimidine-5-carbonitrile::4-oxidanylidene-2-piperidin-1-yl-6-(4-propan-2-ylphenyl)-1H-pyrimidine-5-carbonitrile::4-oxo-2-(1-piperidinyl)-6-(4-propan-2-ylphenyl)-1H-pyrimidine-5-carbonitrile::4-oxo-2-piperidin-1-yl-6-(4-propan-2-ylphenyl)-1H-pyrimidine-5-carbonitrile::MLS000044630::SMR000022574::cid_891760

SMILES: CC(C)c1ccc(cc1)-c1nc([nH]c(=O)c1C#N)N1CCCCC1

InChI Key: InChIKey=RPEQRRUOKCBHNN-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 48941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM48941 (4-hydroxy-6-(4-isopropylphenyl)-2-piperidin-1-ylpy...) Show SMILES CC(C)c1ccc(cc1)-c1nc([nH]c(=O)c1C#N)N1CCCCC1 Show InChI InChI=1S/C19H22N4O/c1-13(2)14-6-8-15(9-7-14)17-16(12-20)18(24)22-19(21-17)23-10-4-3-5-11-23/h6-9,13H,3-5,10-11H2,1-2H3,(H,21,22,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.00175	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2H41PVH
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM48941 (4-hydroxy-6-(4-isopropylphenyl)-2-piperidin-1-ylpy...) Show SMILES CC(C)c1ccc(cc1)-c1nc([nH]c(=O)c1C#N)N1CCCCC1 Show InChI InChI=1S/C19H22N4O/c1-13(2)14-6-8-15(9-7-14)17-16(12-20)18(24)22-19(21-17)23-10-4-3-5-11-23/h6-9,13H,3-5,10-11H2,1-2H3,(H,21,22,24)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.0000236	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2MW2FJG
					More data for this Ligand-Target Pair