BDBM49145 6-(4-o-phenetylpiperazino)sulfonyl-1H-benzo[cd]indol-2-one::6-[4-(2-ethoxyphenyl)piperazin-1-yl]sulfonyl-1H-benzo[cd]indol-2-one::6-[[4-(2-ethoxyphenyl)-1-piperazinyl]sulfonyl]-1H-benzo[cd]indol-2-one::6-{[4-(2-ethoxyphenyl)-1-piperazinyl]sulfonyl}benzo[cd]indol-2(1H)-one::MLS000049638::SMR000076219::cid_2133613

SMILES: CCOc1ccccc1N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23

InChI Key: InChIKey=TXJMLBKNYFETGN-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 49145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM49145 (6-(4-o-phenetylpiperazino)sulfonyl-1H-benzo[cd]ind...) Show SMILES CCOc1ccccc1N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 Show InChI InChI=1S/C23H23N3O4S/c1-2-30-20-9-4-3-8-19(20)25-12-14-26(15-13-25)31(28,29)21-11-10-18-22-16(21)6-5-7-17(22)23(27)24-18/h3-11H,2,12-15H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	9.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2CF9NHH
					More data for this Ligand-Target Pair
Intestinal alkaline phosphatase (Homo sapiens (Human))	BDBM49145 (6-(4-o-phenetylpiperazino)sulfonyl-1H-benzo[cd]ind...) Show SMILES CCOc1ccccc1N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 Show InChI InChI=1S/C23H23N3O4S/c1-2-30-20-9-4-3-8-19(20)25-12-14-26(15-13-25)31(28,29)21-11-10-18-22-16(21)6-5-7-17(22)23(27)24-18/h3-11H,2,12-15H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2X63KDM
					More data for this Ligand-Target Pair
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 (Homo sapiens (Human))	BDBM49145 (6-(4-o-phenetylpiperazino)sulfonyl-1H-benzo[cd]ind...) Show SMILES CCOc1ccccc1N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 Show InChI InChI=1S/C23H23N3O4S/c1-2-30-20-9-4-3-8-19(20)25-12-14-26(15-13-25)31(28,29)21-11-10-18-22-16(21)6-5-7-17(22)23(27)24-18/h3-11H,2,12-15H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	7.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V986KM
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM49145 (6-(4-o-phenetylpiperazino)sulfonyl-1H-benzo[cd]ind...) Show SMILES CCOc1ccccc1N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 Show InChI InChI=1S/C23H23N3O4S/c1-2-30-20-9-4-3-8-19(20)25-12-14-26(15-13-25)31(28,29)21-11-10-18-22-16(21)6-5-7-17(22)23(27)24-18/h3-11H,2,12-15H2,1H3,(H,24,27)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	8.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2H130G1
					More data for this Ligand-Target Pair
Alpi (Rattus norvegicus (Rat))	BDBM49145 (6-(4-o-phenetylpiperazino)sulfonyl-1H-benzo[cd]ind...) Show SMILES CCOc1ccccc1N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 Show InChI InChI=1S/C23H23N3O4S/c1-2-30-20-9-4-3-8-19(20)25-12-14-26(15-13-25)31(28,29)21-11-10-18-22-16(21)6-5-7-17(22)23(27)24-18/h3-11H,2,12-15H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	7.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DB809V
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM49145 (6-(4-o-phenetylpiperazino)sulfonyl-1H-benzo[cd]ind...) Show SMILES CCOc1ccccc1N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 Show InChI InChI=1S/C23H23N3O4S/c1-2-30-20-9-4-3-8-19(20)25-12-14-26(15-13-25)31(28,29)21-11-10-18-22-16(21)6-5-7-17(22)23(27)24-18/h3-11H,2,12-15H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2NS0SCW
					More data for this Ligand-Target Pair