BDBM50012340 11-[2-(4-Benzyl-piperazin-1-yl)-acetyl]-5,11-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one::CHEMBL67381

SMILES: O=C(CN1CCN(Cc2ccccc2)CC1)N1c2ccccc2C(=O)Nc2cccnc12

InChI Key: InChIKey=RJGGRENGKYTGDC-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (RAT)	BDBM50012340 (11-[2-(4-Benzyl-piperazin-1-yl)-acetyl]-5,11-dihyd...) Show SMILES O=C(CN1CCN(Cc2ccccc2)CC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C25H25N5O2/c31-23(18-29-15-13-28(14-16-29)17-19-7-2-1-3-8-19)30-22-11-5-4-9-20(22)25(32)27-21-10-6-12-26-24(21)30/h1-12H,13-18H2,(H,27,32)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-N-Methyl-scopolamine to muscarinic acetylcholine receptor M4 of rat heart NG108-15 cells				J Med Chem 34: 2133-45 (1991) BindingDB Entry DOI: 10.7270/Q2SJ1JKW
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50012340 (11-[2-(4-Benzyl-piperazin-1-yl)-acetyl]-5,11-dihyd...) Show SMILES O=C(CN1CCN(Cc2ccccc2)CC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C25H25N5O2/c31-23(18-29-15-13-28(14-16-29)17-19-7-2-1-3-8-19)30-22-11-5-4-9-20(22)25(32)27-21-10-6-12-26-24(21)30/h1-12H,13-18H2,(H,27,32)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-N-methylscopolamine to muscarinic acetylcholine receptor M3 of transfected rat A9L cells.				J Med Chem 34: 2133-45 (1991) BindingDB Entry DOI: 10.7270/Q2SJ1JKW
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50012340 (11-[2-(4-Benzyl-piperazin-1-yl)-acetyl]-5,11-dihyd...) Show SMILES O=C(CN1CCN(Cc2ccccc2)CC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C25H25N5O2/c31-23(18-29-15-13-28(14-16-29)17-19-7-2-1-3-8-19)30-22-11-5-4-9-20(22)25(32)27-21-10-6-12-26-24(21)30/h1-12H,13-18H2,(H,27,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-N-methylscopolamine to muscarinic acetylcholine receptor M2 of rat heart tissue membrane.				J Med Chem 34: 2133-45 (1991) BindingDB Entry DOI: 10.7270/Q2SJ1JKW
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50012340 (11-[2-(4-Benzyl-piperazin-1-yl)-acetyl]-5,11-dihyd...) Show SMILES O=C(CN1CCN(Cc2ccccc2)CC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C25H25N5O2/c31-23(18-29-15-13-28(14-16-29)17-19-7-2-1-3-8-19)30-22-11-5-4-9-20(22)25(32)27-21-10-6-12-26-24(21)30/h1-12H,13-18H2,(H,27,32)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-N-methylscopolamine to muscarinic acetylcholine receptor M1 of transfected rat A9L cells.				J Med Chem 34: 2133-45 (1991) BindingDB Entry DOI: 10.7270/Q2SJ1JKW
					More data for this Ligand-Target Pair