null

SMILES: Cn1c2ncn(CCCN3CCN(CC3)C(c3ccc(F)cc3)c3ccc(F)cc3)c2c(=O)n(C)c1=O

InChI Key: InChIKey=VOEUXHROHLFPEE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50031297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50031297 (7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...) Show SMILES Cn1c2ncn(CCCN3CCN(CC3)C(c3ccc(F)cc3)c3ccc(F)cc3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C27H30F2N6O2/c1-31-25-24(26(36)32(2)27(31)37)35(18-30-25)13-3-12-33-14-16-34(17-15-33)23(19-4-8-21(28)9-5-19)20-6-10-22(29)11-7-20/h4-11,18,23H,3,12-17H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Compound is evaluated for in vitro receptor binding affinity against H1 receptor				J Med Chem 38: 4026-32 (1995) BindingDB Entry DOI: 10.7270/Q2MK6DJG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50031297 (7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...) Show SMILES Cn1c2ncn(CCCN3CCN(CC3)C(c3ccc(F)cc3)c3ccc(F)cc3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C27H30F2N6O2/c1-31-25-24(26(36)32(2)27(31)37)35(18-30-25)13-3-12-33-14-16-34(17-15-33)23(19-4-8-21(28)9-5-19)20-6-10-22(29)11-7-20/h4-11,18,23H,3,12-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Compound is evaluated for in vitro receptor binding affinity against 5-hydroxytryptamine 1A receptor				J Med Chem 38: 4026-32 (1995) BindingDB Entry DOI: 10.7270/Q2MK6DJG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50031297 (7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...) Show SMILES Cn1c2ncn(CCCN3CCN(CC3)C(c3ccc(F)cc3)c3ccc(F)cc3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C27H30F2N6O2/c1-31-25-24(26(36)32(2)27(31)37)35(18-30-25)13-3-12-33-14-16-34(17-15-33)23(19-4-8-21(28)9-5-19)20-6-10-22(29)11-7-20/h4-11,18,23H,3,12-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Compound is evaluated for in vitro receptor binding affinity against Dopamine receptor D2				J Med Chem 38: 4026-32 (1995) BindingDB Entry DOI: 10.7270/Q2MK6DJG
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50031297 (7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...) Show SMILES Cn1c2ncn(CCCN3CCN(CC3)C(c3ccc(F)cc3)c3ccc(F)cc3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C27H30F2N6O2/c1-31-25-24(26(36)32(2)27(31)37)35(18-30-25)13-3-12-33-14-16-34(17-15-33)23(19-4-8-21(28)9-5-19)20-6-10-22(29)11-7-20/h4-11,18,23H,3,12-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M2				J Med Chem 38: 4026-32 (1995) BindingDB Entry DOI: 10.7270/Q2MK6DJG
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50031297 (7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...) Show SMILES Cn1c2ncn(CCCN3CCN(CC3)C(c3ccc(F)cc3)c3ccc(F)cc3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C27H30F2N6O2/c1-31-25-24(26(36)32(2)27(31)37)35(18-30-25)13-3-12-33-14-16-34(17-15-33)23(19-4-8-21(28)9-5-19)20-6-10-22(29)11-7-20/h4-11,18,23H,3,12-17H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1				J Med Chem 38: 4026-32 (1995) BindingDB Entry DOI: 10.7270/Q2MK6DJG
					More data for this Ligand-Target Pair