BDBM50036963 (R)-4-Carboxy-1-mercaptomethyl-butyl-ammonium::(R)-5-Amino-6-mercapto-hexanoic acid::CHEMBL102006
SMILES: N[C@@H](CS)CCCC(O)=O
InChI Key: InChIKey=ZIPKWPPCKXBHEO-RXMQYKEDSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aminopeptidase A (Homo sapiens (Human)) | BDBM50036963 ((R)-4-Carboxy-1-mercaptomethyl-butyl-ammonium | (R...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inihibitionof aminopeptidase A (APA) | J Med Chem 37: 2950-7 (1994) BindingDB Entry DOI: 10.7270/Q2B8575H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50036963 ((R)-4-Carboxy-1-mercaptomethyl-butyl-ammonium | (R...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Jadavpur University Curated by ChEMBL | Assay Description Inhibition of hog kidney APN using [3H]Tyr1-Leu5-enkephalin as substrate preincubated for 15 mins followed by substrate addition measured after 15 mi... | J Med Chem 61: 6468-6490 (2018) Article DOI: 10.1021/acs.jmedchem.7b00782 BindingDB Entry DOI: 10.7270/Q28S4SHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50036963 ((R)-4-Carboxy-1-mercaptomethyl-butyl-ammonium | (R...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory potency was measured on aminopeptidase N (APN) | J Med Chem 37: 2950-7 (1994) BindingDB Entry DOI: 10.7270/Q2B8575H | |||||||||||
More data for this Ligand-Target Pair |