BDBM50037036 5,7-Dimethoxy-2-[(pyridin-3-ylmethyl)-amino]-benzothiazol-6-ol::CHEMBL420281
SMILES: COc1cc2nc(NCc3cccnc3)sc2c(OC)c1O
InChI Key: InChIKey=AAFZJNQGJYIQOB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thromboxane-A synthase (Rattus norvegicus) | BDBM50037036 (5,7-Dimethoxy-2-[(pyridin-3-ylmethyl)-amino]-benzo...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Company, Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat | J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50037036 (5,7-Dimethoxy-2-[(pyridin-3-ylmethyl)-amino]-benzo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Company, Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat | J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J | |||||||||||
More data for this Ligand-Target Pair |