BDBM50037747 5-[1-Cyclohexyl-2-imidazol-1-yl-3-p-tolyl-prop-(E)-ylideneaminooxy]-pentanoic acid::CHEMBL120250

SMILES: Cc1ccc(CC(\C(=N\OCCCCC(O)=O)C2CCCCC2)n2ccnc2)cc1

InChI Key: InChIKey=BYSGUPLQHXMDFG-SHHOIMCASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037747 (5-[1-Cyclohexyl-2-imidazol-1-yl-3-p-tolyl-prop-(E)...) Show SMILES Cc1ccc(CC(\C(=N\OCCCCC(O)=O)C2CCCCC2)n2ccnc2)cc1 Show InChI InChI=1S/C24H33N3O3/c1-19-10-12-20(13-11-19)17-22(27-15-14-25-18-27)24(21-7-3-2-4-8-21)26-30-16-6-5-9-23(28)29/h10-15,18,21-22H,2-9,16-17H2,1H3,(H,28,29)/b26-24+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade				J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50037747 (5-[1-Cyclohexyl-2-imidazol-1-yl-3-p-tolyl-prop-(E)...) Show SMILES Cc1ccc(CC(\C(=N\OCCCCC(O)=O)C2CCCCC2)n2ccnc2)cc1 Show InChI InChI=1S/C24H33N3O3/c1-19-10-12-20(13-11-19)17-22(27-15-14-25-18-27)24(21-7-3-2-4-8-21)26-30-16-6-5-9-23(28)29/h10-15,18,21-22H,2-9,16-17H2,1H3,(H,28,29)/b26-24+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL					Assay Description In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human platelets				J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD
					More data for this Ligand-Target Pair