BDBM50037752 5-[1-Cyclohexyl-2-imidazol-1-yl-3-pyridin-2-yl-prop-(E)-ylideneaminooxy]-pentanoic acid::CHEMBL120228

SMILES: OC(=O)CCCCO\N=C(\C(Cc1ccccn1)n1ccnc1)C1CCCCC1

InChI Key: InChIKey=RGKFRDSUSCQIBX-YYDJUVGSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037752 (5-[1-Cyclohexyl-2-imidazol-1-yl-3-pyridin-2-yl-pro...) Show SMILES OC(=O)CCCCO\N=C(\C(Cc1ccccn1)n1ccnc1)C1CCCCC1 Show InChI InChI=1S/C22H30N4O3/c27-21(28)11-5-7-15-29-25-22(18-8-2-1-3-9-18)20(26-14-13-23-17-26)16-19-10-4-6-12-24-19/h4,6,10,12-14,17-18,20H,1-3,5,7-9,11,15-16H2,(H,27,28)/b25-22+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade				J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50037752 (5-[1-Cyclohexyl-2-imidazol-1-yl-3-pyridin-2-yl-pro...) Show SMILES OC(=O)CCCCO\N=C(\C(Cc1ccccn1)n1ccnc1)C1CCCCC1 Show InChI InChI=1S/C22H30N4O3/c27-21(28)11-5-7-15-29-25-22(18-8-2-1-3-9-18)20(26-14-13-23-17-26)16-19-10-4-6-12-24-19/h4,6,10,12-14,17-18,20H,1-3,5,7-9,11,15-16H2,(H,27,28)/b25-22+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL					Assay Description In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human platelets				J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD
					More data for this Ligand-Target Pair