BDBM50037762 5-[2-Imidazol-1-yl-1-phenyl-eth-(E)-ylideneaminooxy]-pentanoic acid::CHEMBL120947
SMILES: OC(=O)CCCCO\N=C(\Cn1ccnc1)c1ccccc1
InChI Key: InChIKey=MUDPLRYELCSFII-SDXDJHTJSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thromboxane-A synthase (Rattus norvegicus) | BDBM50037762 (5-[2-Imidazol-1-yl-1-phenyl-eth-(E)-ylideneaminoox...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade | J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50037762 (5-[2-Imidazol-1-yl-1-phenyl-eth-(E)-ylideneaminoox...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL | Assay Description In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human platelets | J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD | |||||||||||
More data for this Ligand-Target Pair |