BDBM50037763 6-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneaminooxy]-hexanoic acid::CHEMBL120284

SMILES: OC(=O)CCCCCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1

InChI Key: InChIKey=HYJNXVDECKJAJZ-SHHOIMCASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50037763 (6-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneam...) Show SMILES OC(=O)CCCCCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O3/c28-23(29)14-8-3-9-17-30-26-24(21-12-6-2-7-13-21)22(27-16-15-25-19-27)18-20-10-4-1-5-11-20/h1-2,4-7,10-13,15-16,19,22H,3,8-9,14,17-18H2,(H,28,29)/b26-24+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL					Assay Description In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human platelets				J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037763 (6-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneam...) Show SMILES OC(=O)CCCCCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O3/c28-23(29)14-8-3-9-17-30-26-24(21-12-6-2-7-13-21)22(27-16-15-25-19-27)18-20-10-4-1-5-11-20/h1-2,4-7,10-13,15-16,19,22H,3,8-9,14,17-18H2,(H,28,29)/b26-24+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade				J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD
					More data for this Ligand-Target Pair