BDBM50037768 5-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneaminooxy]-3,3-dimethyl-pentanoic acid::CHEMBL123307

SMILES: CC(C)(CCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1)CC(O)=O

InChI Key: InChIKey=CVNWEPXFYHLRCJ-SOYKGTTHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037768 (5-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneam...) Show SMILES CC(C)(CCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1)CC(O)=O Show InChI InChI=1S/C25H29N3O3/c1-25(2,18-23(29)30)13-16-31-27-24(21-11-7-4-8-12-21)22(28-15-14-26-19-28)17-20-9-5-3-6-10-20/h3-12,14-15,19,22H,13,16-18H2,1-2H3,(H,29,30)/b27-24+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade				J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50037768 (5-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneam...) Show SMILES CC(C)(CCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1)CC(O)=O Show InChI InChI=1S/C25H29N3O3/c1-25(2,18-23(29)30)13-16-31-27-24(21-11-7-4-8-12-21)22(28-15-14-26-19-28)17-20-9-5-3-6-10-20/h3-12,14-15,19,22H,13,16-18H2,1-2H3,(H,29,30)/b27-24+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia-Farmitalia Carlo Erba Curated by ChEMBL					Assay Description In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human platelets				J Med Chem 37: 3588-604 (1994) BindingDB Entry DOI: 10.7270/Q2C24VFD
					More data for this Ligand-Target Pair