BDBM50043460 CHEMBL134286::{Cyclopropylmethyl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-amino}-phenyl-acetic acid

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC1CC1)C(C(O)=O)c1ccccc1

InChI Key: InChIKey=FGABYXXTYUSGCF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (RAT)	BDBM50043460 (CHEMBL134286 | {Cyclopropylmethyl-[4-(2-ethyl-5,7-...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC1CC1)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C29H32N4O2/c1-4-25-31-26-19(2)16-20(3)30-28(26)33(25)18-22-12-14-24(15-13-22)32(17-21-10-11-21)27(29(34)35)23-8-6-5-7-9-23/h5-9,12-16,21,27H,4,10-11,17-18H2,1-3H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043460 (CHEMBL134286 | {Cyclopropylmethyl-[4-(2-ethyl-5,7-...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC1CC1)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C29H32N4O2/c1-4-25-31-26-19(2)16-20(3)30-28(26)33(25)18-22-12-14-24(15-13-22)32(17-21-10-11-21)27(29(34)35)23-8-6-5-7-9-23/h5-9,12-16,21,27H,4,10-11,17-18H2,1-3H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair