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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-2 angiotensin II receptor' and Ligand = 'BDBM50043460'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-2 angiotensin II receptor


(RAT)		BDBM50043460
PNG
(CHEMBL134286 | {Cyclopropylmethyl-[4-(2-ethyl-5,7-...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC1CC1)C(C(O)=O)c1ccccc1
Show InChI InChI=1S/C29H32N4O2/c1-4-25-31-26-19(2)16-20(3)30-28(26)33(25)18-22-12-14-24(15-13-22)32(17-21-10-11-21)27(29(34)35)23-8-6-5-7-9-23/h5-9,12-16,21,27H,4,10-11,17-18H2,1-3H3,(H,34,35)
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PC sid
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PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair