BDBM50050731 CHEMBL289839::N-[(1R,2S)-2-(4-Hydroxy-phenyl)-indan-1-yl]-2,2-diphenyl-acetamide
SMILES: Oc1ccc(cc1)[C@@H]1Cc2ccccc2[C@@H]1NC(=O)C(c1ccccc1)c1ccccc1
InChI Key: InChIKey=ZPORBGGQIAIHNC-XCZPVHLTSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sterol O-acyltransferase, Soat (Rattus norvegicus) | BDBM50050731 (CHEMBL289839 | N-[(1R,2S)-2-(4-Hydroxy-phenyl)-ind...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against Acyl coenzyme A:cholesterol acyltransferase 1 from rat hepatic microsomes at 10 microM | J Med Chem 39: 1704-19 (1996) Article DOI: 10.1021/jm950833d BindingDB Entry DOI: 10.7270/Q2QN65V7 | |||||||||||
More data for this Ligand-Target Pair |