BDBM50050731 CHEMBL289839::N-[(1R,2S)-2-(4-Hydroxy-phenyl)-indan-1-yl]-2,2-diphenyl-acetamide

SMILES: Oc1ccc(cc1)[C@@H]1Cc2ccccc2[C@@H]1NC(=O)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=ZPORBGGQIAIHNC-XCZPVHLTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50050731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50050731 (CHEMBL289839 | N-[(1R,2S)-2-(4-Hydroxy-phenyl)-ind...) Show SMILES Oc1ccc(cc1)[C@@H]1Cc2ccccc2[C@@H]1NC(=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H25NO2/c31-24-17-15-20(16-18-24)26-19-23-13-7-8-14-25(23)28(26)30-29(32)27(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-18,26-28,31H,19H2,(H,30,32)/t26-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against Acyl coenzyme A:cholesterol acyltransferase 1 from rat hepatic microsomes at 10 microM				J Med Chem 39: 1704-19 (1996) Article DOI: 10.1021/jm950833d BindingDB Entry DOI: 10.7270/Q2QN65V7
					More data for this Ligand-Target Pair