BDBM50087248 3-Chloro-4-[(7-chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-benzenesulfonamide::CHEMBL158827

SMILES: NS(=O)(=O)c1ccc(NCc2cc(=O)oc3cc(Cl)ccc23)c(Cl)c1

InChI Key: InChIKey=ANVRZEGNTAGLOH-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50087248 (3-Chloro-4-[(7-chloro-2-oxo-2H-chromen-4-ylmethyl)...) Show SMILES NS(=O)(=O)c1ccc(NCc2cc(=O)oc3cc(Cl)ccc23)c(Cl)c1 Show InChI InChI=1S/C16H12Cl2N2O4S/c17-10-1-3-12-9(5-16(21)24-15(12)6-10)8-20-14-4-2-11(7-13(14)18)25(19,22)23/h1-7,20H,8H2,(H2,19,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase II				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50087248 (3-Chloro-4-[(7-chloro-2-oxo-2H-chromen-4-ylmethyl)...) Show SMILES NS(=O)(=O)c1ccc(NCc2cc(=O)oc3cc(Cl)ccc23)c(Cl)c1 Show InChI InChI=1S/C16H12Cl2N2O4S/c17-10-1-3-12-9(5-16(21)24-15(12)6-10)8-20-14-4-2-11(7-13(14)18)25(19,22)23/h1-7,20H,8H2,(H2,19,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of bovine Carbonic anhydrase IV determined by esterase method				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50087248 (3-Chloro-4-[(7-chloro-2-oxo-2H-chromen-4-ylmethyl)...) Show SMILES NS(=O)(=O)c1ccc(NCc2cc(=O)oc3cc(Cl)ccc23)c(Cl)c1 Show InChI InChI=1S/C16H12Cl2N2O4S/c17-10-1-3-12-9(5-16(21)24-15(12)6-10)8-20-14-4-2-11(7-13(14)18)25(19,22)23/h1-7,20H,8H2,(H2,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase I				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair