BDBM50087255 5-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-[1,3,4]thiadiazole-2-sulfonic acid amide::CHEMBL161560

SMILES: NS(=O)(=O)c1nnc(NCc2cc(=O)oc3cc(Cl)ccc23)s1

InChI Key: InChIKey=GKSHXHOOVHLDDC-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50087255 (5-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-[...) Show SMILES NS(=O)(=O)c1nnc(NCc2cc(=O)oc3cc(Cl)ccc23)s1 Show InChI InChI=1S/C12H9ClN4O4S2/c13-7-1-2-8-6(3-10(18)21-9(8)4-7)5-15-11-16-17-12(22-11)23(14,19)20/h1-4H,5H2,(H,15,16)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase II				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50087255 (5-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-[...) Show SMILES NS(=O)(=O)c1nnc(NCc2cc(=O)oc3cc(Cl)ccc23)s1 Show InChI InChI=1S/C12H9ClN4O4S2/c13-7-1-2-8-6(3-10(18)21-9(8)4-7)5-15-11-16-17-12(22-11)23(14,19)20/h1-4H,5H2,(H,15,16)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of bovine Carbonic anhydrase IV determined by esterase method				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50087255 (5-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-[...) Show SMILES NS(=O)(=O)c1nnc(NCc2cc(=O)oc3cc(Cl)ccc23)s1 Show InChI InChI=1S/C12H9ClN4O4S2/c13-7-1-2-8-6(3-10(18)21-9(8)4-7)5-15-11-16-17-12(22-11)23(14,19)20/h1-4H,5H2,(H,15,16)(H2,14,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase I				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair