BDBM50087257 4-{2-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-ethyl}-benzenesulfonamide::CHEMBL350430

SMILES: NS(=O)(=O)c1ccc(CCNCc2cc(=O)oc3cc(Cl)ccc23)cc1

InChI Key: InChIKey=SGZAPZZACULLGE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50087257 (4-{2-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino...) Show SMILES NS(=O)(=O)c1ccc(CCNCc2cc(=O)oc3cc(Cl)ccc23)cc1 Show InChI InChI=1S/C18H17ClN2O4S/c19-14-3-6-16-13(9-18(22)25-17(16)10-14)11-21-8-7-12-1-4-15(5-2-12)26(20,23)24/h1-6,9-10,21H,7-8,11H2,(H2,20,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase II				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50087257 (4-{2-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino...) Show SMILES NS(=O)(=O)c1ccc(CCNCc2cc(=O)oc3cc(Cl)ccc23)cc1 Show InChI InChI=1S/C18H17ClN2O4S/c19-14-3-6-16-13(9-18(22)25-17(16)10-14)11-21-8-7-12-1-4-15(5-2-12)26(20,23)24/h1-6,9-10,21H,7-8,11H2,(H2,20,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of bovine Carbonic anhydrase IV determined by esterase method				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50087257 (4-{2-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino...) Show SMILES NS(=O)(=O)c1ccc(CCNCc2cc(=O)oc3cc(Cl)ccc23)cc1 Show InChI InChI=1S/C18H17ClN2O4S/c19-14-3-6-16-13(9-18(22)25-17(16)10-14)11-21-8-7-12-1-4-15(5-2-12)26(20,23)24/h1-6,9-10,21H,7-8,11H2,(H2,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase I				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair