BDBM50087262 5-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-ylamino)-[1,3,4]thiadiazole-2-sulfonic acid amide::CHEMBL161205

SMILES: NS(=O)(=O)c1nnc(NN2C(=O)c3cccnc3C2=O)s1

InChI Key: InChIKey=LZESFUBKTSVDDD-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50087262 (5-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...) Show SMILES NS(=O)(=O)c1nnc(NN2C(=O)c3cccnc3C2=O)s1 Show InChI InChI=1S/C9H6N6O4S2/c10-21(18,19)9-13-12-8(20-9)14-15-6(16)4-2-1-3-11-5(4)7(15)17/h1-3H,(H,12,14)(H2,10,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase II				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50087262 (5-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...) Show SMILES NS(=O)(=O)c1nnc(NN2C(=O)c3cccnc3C2=O)s1 Show InChI InChI=1S/C9H6N6O4S2/c10-21(18,19)9-13-12-8(20-9)14-15-6(16)4-2-1-3-11-5(4)7(15)17/h1-3H,(H,12,14)(H2,10,18,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of bovine Carbonic anhydrase IV determined by esterase method				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50087262 (5-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...) Show SMILES NS(=O)(=O)c1nnc(NN2C(=O)c3cccnc3C2=O)s1 Show InChI InChI=1S/C9H6N6O4S2/c10-21(18,19)9-13-12-8(20-9)14-15-6(16)4-2-1-3-11-5(4)7(15)17/h1-3H,(H,12,14)(H2,10,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase I				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair