BDBM50087264 5-[(Z)-7-Chloro-2-oxo-2H-chromen-4-ylmethylimino]-4-methyl-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide::CHEMBL161443

SMILES: Cn1nc(s\c1=N/Cc1cc(=O)oc2cc(Cl)ccc12)S(N)(=O)=O

InChI Key: InChIKey=OJIHLNZBFOHKCT-VBKFSLOCSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50087264 (5-[(Z)-7-Chloro-2-oxo-2H-chromen-4-ylmethylimino]-...) Show SMILES Cn1nc(s\c1=N/Cc1cc(=O)oc2cc(Cl)ccc12)S(N)(=O)=O Show InChI InChI=1S/C13H11ClN4O4S2/c1-18-12(23-13(17-18)24(15,20)21)16-6-7-4-11(19)22-10-5-8(14)2-3-9(7)10/h2-5H,6H2,1H3,(H2,15,20,21)/b16-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase II				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50087264 (5-[(Z)-7-Chloro-2-oxo-2H-chromen-4-ylmethylimino]-...) Show SMILES Cn1nc(s\c1=N/Cc1cc(=O)oc2cc(Cl)ccc12)S(N)(=O)=O Show InChI InChI=1S/C13H11ClN4O4S2/c1-18-12(23-13(17-18)24(15,20)21)16-6-7-4-11(19)22-10-5-8(14)2-3-9(7)10/h2-5H,6H2,1H3,(H2,15,20,21)/b16-12-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of bovine Carbonic anhydrase IV determined by esterase method				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50087264 (5-[(Z)-7-Chloro-2-oxo-2H-chromen-4-ylmethylimino]-...) Show SMILES Cn1nc(s\c1=N/Cc1cc(=O)oc2cc(Cl)ccc12)S(N)(=O)=O Show InChI InChI=1S/C13H11ClN4O4S2/c1-18-12(23-13(17-18)24(15,20)21)16-6-7-4-11(19)22-10-5-8(14)2-3-9(7)10/h2-5H,6H2,1H3,(H2,15,20,21)/b16-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of human cloned Carbonic anhydrase I				Bioorg Med Chem Lett 10: 673-6 (2000) BindingDB Entry DOI: 10.7270/Q2RV0P61
					More data for this Ligand-Target Pair