null

SMILES: CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1

InChI Key: InChIKey=LXKHXLQQHKRMFP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109637   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50109637 (4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...) Show SMILES CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1 Show InChI InChI=1S/C22H28N3O7P/c1-3-32-33(29,19-11-9-18(30-2)10-12-19)25-14-13-24(15-20(25)21(26)23-28)22(27)31-16-17-7-5-4-6-8-17/h4-12,20,28H,3,13-16H2,1-2H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50109637 (4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...) Show SMILES CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1 Show InChI InChI=1S/C22H28N3O7P/c1-3-32-33(29,19-11-9-18(30-2)10-12-19)25-14-13-24(15-20(25)21(26)23-28)22(27)31-16-17-7-5-4-6-8-17/h4-12,20,28H,3,13-16H2,1-2H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50109637 (4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...) Show SMILES CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1 Show InChI InChI=1S/C22H28N3O7P/c1-3-32-33(29,19-11-9-18(30-2)10-12-19)25-14-13-24(15-20(25)21(26)23-28)22(27)31-16-17-7-5-4-6-8-17/h4-12,20,28H,3,13-16H2,1-2H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50109637 (4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...) Show SMILES CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1 Show InChI InChI=1S/C22H28N3O7P/c1-3-32-33(29,19-11-9-18(30-2)10-12-19)25-14-13-24(15-20(25)21(26)23-28)22(27)31-16-17-7-5-4-6-8-17/h4-12,20,28H,3,13-16H2,1-2H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 9 (Homo sapiens (Human))	BDBM50109637 (4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...) Show SMILES CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1 Show InChI InChI=1S/C22H28N3O7P/c1-3-32-33(29,19-11-9-18(30-2)10-12-19)25-14-13-24(15-20(25)21(26)23-28)22(27)31-16-17-7-5-4-6-8-17/h4-12,20,28H,3,13-16H2,1-2H3,(H,23,26)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair