BDBM50123813 5-Bromo-2-methoxy-6-methylamino-N-(1-methyl-4-propyl-[1,4]diazepan-6-yl)-nicotinamide::CHEMBL351377

SMILES: CCCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC

InChI Key: InChIKey=OGSGEZFHFQQZBX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50123813 (5-Bromo-2-methoxy-6-methylamino-N-(1-methyl-4-prop...) Show SMILES CCCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC Show InChI InChI=1S/C17H28BrN5O2/c1-5-6-23-8-7-22(3)10-12(11-23)20-16(24)13-9-14(18)15(19-2)21-17(13)25-4/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47.1	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of the binding of radioligand [3H]spiperone to dopamine receptor D2 in rat brain synaptic membrane				J Med Chem 46: 702-15 (2003) Article DOI: 10.1021/jm020270n BindingDB Entry DOI: 10.7270/Q25H7H06
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50123813 (5-Bromo-2-methoxy-6-methylamino-N-(1-methyl-4-prop...) Show SMILES CCCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC Show InChI InChI=1S/C17H28BrN5O2/c1-5-6-23-8-7-22(3)10-12(11-23)20-16(24)13-9-14(18)15(19-2)21-17(13)25-4/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...				J Med Chem 46: 702-15 (2003) Article DOI: 10.1021/jm020270n BindingDB Entry DOI: 10.7270/Q25H7H06
					More data for this Ligand-Target Pair