BDBM50127228 2-({6-[(2-Mercapto-ethylamino)-methyl]-4-naphthalen-1-yl-pyridin-2-ylmethyl}-amino)-ethanethiol::CHEMBL39572

SMILES: SCCNCc1cc(cc(CNCCS)n1)-c1cccc2ccccc12

InChI Key: InChIKey=ZTNYDRGHMAAJMX-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50127228 (2-({6-[(2-Mercapto-ethylamino)-methyl]-4-naphthale...) Show SMILES SCCNCc1cc(cc(CNCCS)n1)-c1cccc2ccccc12 Show InChI InChI=1S/C21H25N3S2/c25-10-8-22-14-18-12-17(13-19(24-18)15-23-9-11-26)21-7-3-5-16-4-1-2-6-20(16)21/h1-7,12-13,22-23,25-26H,8-11,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of [3H]-farnesyl pyrophosphate binding to human farnesyltransferase				Bioorg Med Chem Lett 13: 1523-6 (2003) BindingDB Entry DOI: 10.7270/Q2QZ29BR
					More data for this Ligand-Target Pair