Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50127228'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50127228 (2-({6-[(2-Mercapto-ethylamino)-methyl]-4-naphthale...) Show SMILES SCCNCc1cc(cc(CNCCS)n1)-c1cccc2ccccc12 Show InChI InChI=1S/C21H25N3S2/c25-10-8-22-14-18-12-17(13-19(24-18)15-23-9-11-26)21-7-3-5-16-4-1-2-6-20(16)21/h1-7,12-13,22-23,25-26H,8-11,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of [3H]-farnesyl pyrophosphate binding to human farnesyltransferase				Bioorg Med Chem Lett 13: 1523-6 (2003) BindingDB Entry DOI: 10.7270/Q2QZ29BR
					More data for this Ligand-Target Pair