BDBM50135621 4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid::CHEMBL329311

SMILES: NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)C(O)=O)s1

InChI Key: InChIKey=PSXHCIPOZRAYGB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50135621 (4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)C(O)=O)s1 Show InChI InChI=1S/C9H8N4O6S3/c10-21(16,17)9-12-11-8(20-9)13-22(18,19)6-3-1-5(2-4-6)7(14)15/h1-4H,(H,11,13)(H,14,15)(H2,10,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human carbonic anhydrase II				Bioorg Med Chem Lett 13: 2867-73 (2003) BindingDB Entry DOI: 10.7270/Q2BR8SQ8
					More data for this Ligand-Target Pair				3D Structure (docked)
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50135621 (4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)C(O)=O)s1 Show InChI InChI=1S/C9H8N4O6S3/c10-21(16,17)9-12-11-8(20-9)13-22(18,19)6-3-1-5(2-4-6)7(14)15/h1-4H,(H,11,13)(H,14,15)(H2,10,16,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung				Bioorg Med Chem Lett 13: 2867-73 (2003) BindingDB Entry DOI: 10.7270/Q2BR8SQ8
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50135621 (4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)C(O)=O)s1 Show InChI InChI=1S/C9H8N4O6S3/c10-21(16,17)9-12-11-8(20-9)13-22(18,19)6-3-1-5(2-4-6)7(14)15/h1-4H,(H,11,13)(H,14,15)(H2,10,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human carbonic anhydrase I (hCA I)				Bioorg Med Chem Lett 13: 2867-73 (2003) BindingDB Entry DOI: 10.7270/Q2BR8SQ8
					More data for this Ligand-Target Pair