BDBM50148123 4-[3-(3,5-Bis-trifluoromethyl-phenoxy)-propyl]-1H-imidazole::CHEMBL322145
SMILES: FC(F)(F)c1cc(OCCCc2cnc[nH]2)cc(c1)C(F)(F)F
InChI Key: InChIKey=DFJKWRRWRYTYFG-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50148123 (4-[3-(3,5-Bis-trifluoromethyl-phenoxy)-propyl]-1H-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description In vitro inhibitory activity against against histamine H3 receptor using [3H]-Histamine as radioligand from rat cerebral cortex synaptosomes | J Med Chem 47: 3264-74 (2004) Article DOI: 10.1021/jm031141p BindingDB Entry DOI: 10.7270/Q2F47NK5 | |||||||||||
More data for this Ligand-Target Pair |