Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50148123'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50148123 (4-[3-(3,5-Bis-trifluoromethyl-phenoxy)-propyl]-1H-...) Show SMILES FC(F)(F)c1cc(OCCCc2cnc[nH]2)cc(c1)C(F)(F)F Show InChI InChI=1S/C14H12F6N2O/c15-13(16,17)9-4-10(14(18,19)20)6-12(5-9)23-3-1-2-11-7-21-8-22-11/h4-8H,1-3H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibitory activity against against histamine H3 receptor using [3H]-Histamine as radioligand from rat cerebral cortex synaptosomes				J Med Chem 47: 3264-74 (2004) Article DOI: 10.1021/jm031141p BindingDB Entry DOI: 10.7270/Q2F47NK5
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