null
SMILES: Cc1ccncc1-c1cc(F)cc(c1)-n1nnc(n1)-c1ncc[nH]1
InChI Key: InChIKey=CZOBXSJMLFQPBT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM50155006 (3-{3-Fluoro-5-[5-(1H-imidazol-2-yl)-tetrazol-2-yl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica... | Bioorg Med Chem Lett 14: 5481-4 (2004) Article DOI: 10.1016/j.bmcl.2004.09.018 BindingDB Entry DOI: 10.7270/Q25M657V | |||||||||||
More data for this Ligand-Target Pair |