null
SMILES: CC(C)CC(=O)c1ccc(OCCCCSc2ccncc2)c(C)c1O
InChI Key: InChIKey=BBMHENISQZYUSJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50155701 (1-{2-Hydroxy-3-methyl-4-[4-(pyridin-4-ylsulfanyl)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]-GTP gama S binding assay | Bioorg Med Chem Lett 14: 5867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.09.028 BindingDB Entry DOI: 10.7270/Q2XW4J94 | |||||||||||
More data for this Ligand-Target Pair |