BDBM50167273 CHEMBL3797316
SMILES: CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OC(C)(C)C(O)=O)c2ccc(C)cc2n1
InChI Key: InChIKey=MCBLPJPMVOVJCO-SFHVURJKSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Purinergic receptor P2Y12 (Homo sapiens (Human)) | BDBM50167273 (CHEMBL3797316) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Galecto Biotech Curated by ChEMBL | Assay Description Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of ADP-induced platelet aggregation measured for 5 mins by lig... | Bioorg Med Chem Lett 26: 2739-2754 (2016) Article DOI: 10.1016/j.bmcl.2016.04.030 BindingDB Entry DOI: 10.7270/Q2FF3V86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purinergic receptor P2Y12 (Homo sapiens (Human)) | BDBM50167273 (CHEMBL3797316) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Galecto Biotech Curated by ChEMBL | Assay Description Displacement of [3H]-2-Mes-ADP from human P2Y12 receptor | Bioorg Med Chem Lett 26: 2739-2754 (2016) Article DOI: 10.1016/j.bmcl.2016.04.030 BindingDB Entry DOI: 10.7270/Q2FF3V86 | |||||||||||
More data for this Ligand-Target Pair |