null
SMILES: COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)C4CCCCC4)cc3)c2cc1OC
InChI Key: InChIKey=UNMJHOVRTAPNDI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50184859![]() (CHEMBL204120 | N-Cyclohexylcarbonyl-N'-{4-[(6,7-di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 233 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of c-kit receptor phosphorylation in M07e cell | J Med Chem 49: 2186-92 (2006) Article DOI: 10.1021/jm0506423 BindingDB Entry DOI: 10.7270/Q2NC60TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM50184859![]() (CHEMBL204120 | N-Cyclohexylcarbonyl-N'-{4-[(6,7-di...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of PDGFR alpha phosphorylation in G292 cell | J Med Chem 49: 2186-92 (2006) Article DOI: 10.1021/jm0506423 BindingDB Entry DOI: 10.7270/Q2NC60TB | |||||||||||
More data for this Ligand-Target Pair |