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SMILES: COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)C4CCCCC4)cc3)c2cc1OC

InChI Key: InChIKey=UNMJHOVRTAPNDI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184859   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50184859
PNG
(CHEMBL204120 | N-Cyclohexylcarbonyl-N'-{4-[(6,7-di...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)C4CCCCC4)cc3)c2cc1OC
Show InChI InChI=1S/C25H27N3O4S/c1-30-22-14-19-20(15-23(22)31-2)26-13-12-21(19)32-18-10-8-17(9-11-18)27-25(33)28-24(29)16-6-4-3-5-7-16/h8-16H,3-7H2,1-2H3,(H2,27,28,29,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 233n/an/an/an/an/an/a



Kirin Brewery Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-kit receptor phosphorylation in M07e cell


J Med Chem 49: 2186-92 (2006)


Article DOI: 10.1021/jm0506423
BindingDB Entry DOI: 10.7270/Q2NC60TB
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor alpha


(Homo sapiens (Human))
BDBM50184859
PNG
(CHEMBL204120 | N-Cyclohexylcarbonyl-N'-{4-[(6,7-di...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)C4CCCCC4)cc3)c2cc1OC
Show InChI InChI=1S/C25H27N3O4S/c1-30-22-14-19-20(15-23(22)31-2)26-13-12-21(19)32-18-10-8-17(9-11-18)27-25(33)28-24(29)16-6-4-3-5-7-16/h8-16H,3-7H2,1-2H3,(H2,27,28,29,33)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Kirin Brewery Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of PDGFR alpha phosphorylation in G292 cell


J Med Chem 49: 2186-92 (2006)


Article DOI: 10.1021/jm0506423
BindingDB Entry DOI: 10.7270/Q2NC60TB
More data for this
Ligand-Target Pair