BDBM50208879 2,6-diaminopurine::9H-Purine-2,6-diamine0.5M H2SO4::CHEMBL388596
SMILES: Nc1nc(N)c2[nH]cnc2n1
InChI Key: InChIKey=MSSXOMSJDRHRMC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Guanine deaminase (Homo sapiens (Human)) | BDBM50208879![]() (2,6-diaminopurine | 9H-Purine-2,6-diamine0.5M H2SO...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey Curated by ChEMBL | Assay Description Inhibition of GDA by colorimetric assay | Bioorg Med Chem 18: 6748-55 (2010) Article DOI: 10.1016/j.bmc.2010.07.054 BindingDB Entry DOI: 10.7270/Q25T3KPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide dependent protein kinase-1 (Homo sapiens (Human)) | BDBM50208879![]() (2,6-diaminopurine | 9H-Purine-2,6-diamine0.5M H2SO...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi... | ACS Med Chem Lett 1: 439-442 (2010) Article DOI: 10.1021/ml100136n BindingDB Entry DOI: 10.7270/Q22807WJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50208879![]() (2,6-diaminopurine | 9H-Purine-2,6-diamine0.5M H2SO...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Charles University Curated by ChEMBL | Assay Description Inhibition of purified Cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis (precipitation at the higher concentra... | J Med Chem 40: 408-12 (1997) Article DOI: 10.1021/jm960666x BindingDB Entry DOI: 10.7270/Q2GF0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM50208879![]() (2,6-diaminopurine | 9H-Purine-2,6-diamine0.5M H2SO...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center Curated by ChEMBL | Assay Description Inhibition of human xanthine oxidase | Bioorg Med Chem 15: 3450-6 (2007) Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G | |||||||||||
More data for this Ligand-Target Pair |