BDBM50211642 CHEMBL397209::Methyl(1,2,3,6-tetrahydropyridinium-4-yl)phosphinate::methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid

SMILES: CP(O)(=O)C1=CCNCC1

InChI Key: InChIKey=MFUKVPOVVKKLRQ-UHFFFAOYSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50211642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human))	BDBM50211642 (CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...) Show SMILES CP(O)(=O)C1=CCNCC1 |t:4| Show InChI InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
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GABA-B receptor 1/2 (Homo sapiens (Human))	BDBM50211642 (CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...) Show SMILES CP(O)(=O)C1=CCNCC1 |t:4| Show InChI InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human recombinant GABAb 1b/2 receptor expressed in Xenopus laevis oocytes co-expressing GIRK1/4 assessed as inhibition of GABA...				ACS Med Chem Lett 2: 11-16 (2011) Article DOI: 10.1021/ml1001344 BindingDB Entry DOI: 10.7270/Q2FX79QR
					More data for this Ligand-Target Pair
GABA-B receptor 1/2 (Rattus norvegicus (Rat))	BDBM50211642 (CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...) Show SMILES CP(O)(=O)C1=CCNCC1 |t:4| Show InChI InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat hippocampal Gamma-aminobutyric acid type B receptor (weak agonist)				Bioorg Med Chem Lett 6: 2073-2076 (1996) Article DOI: 10.1016/0960-894X(96)00364-2 BindingDB Entry DOI: 10.7270/Q2DV1KC9
					More data for this Ligand-Target Pair
GABA-C receptor (Homo sapiens (Human))	BDBM50211642 (CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...) Show SMILES CP(O)(=O)C1=CCNCC1 |t:4| Show InChI InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...				ACS Med Chem Lett 2: 11-16 (2011) Article DOI: 10.1021/ml1001344 BindingDB Entry DOI: 10.7270/Q2FX79QR
					More data for this Ligand-Target Pair
GABA-C receptor (Homo sapiens (Human))	BDBM50211642 (CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...) Show SMILES CP(O)(=O)C1=CCNCC1 |t:4| Show InChI InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Antagonist activity at GABAC rho1 receptor (unknown origin)				ACS Med Chem Lett 4: 402-7 (2013) Article DOI: 10.1021/ml300476v BindingDB Entry DOI: 10.7270/Q27H1KXG
					More data for this Ligand-Target Pair
GABA receptor rho-2 subunit (Homo sapiens (Human))	BDBM50211642 (CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...) Show SMILES CP(O)(=O)C1=CCNCC1 |t:4| Show InChI InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...				ACS Med Chem Lett 2: 11-16 (2011) Article DOI: 10.1021/ml1001344 BindingDB Entry DOI: 10.7270/Q2FX79QR
					More data for this Ligand-Target Pair