BDBM50239414 CHEMBL4073330

SMILES: Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)oc12

InChI Key: InChIKey=FSLWZIRTOUAUNP-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50239414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50239414 (CHEMBL4073330) Show SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)oc12 Show InChI InChI=1S/C24H26N4O4/c29-22-5-4-21(20-3-6-23(30)32-24(20)22)27-14-12-26(13-15-27)10-1-2-16-31-19-8-11-28-18(17-19)7-9-25-28/h3-9,11,17,29H,1-2,10,12-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Erlangen-Nuernberg Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D3R expressed in CHO cell membranes by radioligand binding assay				J Med Chem 60: 4693-4713 (2017) Article DOI: 10.1021/acs.jmedchem.7b00363 BindingDB Entry DOI: 10.7270/Q2QC05NH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50239414 (CHEMBL4073330) Show SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)oc12 Show InChI InChI=1S/C24H26N4O4/c29-22-5-4-21(20-3-6-23(30)32-24(20)22)27-14-12-26(13-15-27)10-1-2-16-31-19-8-11-28-18(17-19)7-9-25-28/h3-9,11,17,29H,1-2,10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Erlangen-Nuernberg Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2SR expressed in CHO cell membranes by radioligand binding assay				J Med Chem 60: 4693-4713 (2017) Article DOI: 10.1021/acs.jmedchem.7b00363 BindingDB Entry DOI: 10.7270/Q2QC05NH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50239414 (CHEMBL4073330) Show SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)oc12 Show InChI InChI=1S/C24H26N4O4/c29-22-5-4-21(20-3-6-23(30)32-24(20)22)27-14-12-26(13-15-27)10-1-2-16-31-19-8-11-28-18(17-19)7-9-25-28/h3-9,11,17,29H,1-2,10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Erlangen-Nuernberg Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2LR expressed in CHO cell membranes by radioligand binding assay				J Med Chem 60: 4693-4713 (2017) Article DOI: 10.1021/acs.jmedchem.7b00363 BindingDB Entry DOI: 10.7270/Q2QC05NH
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50239414 (CHEMBL4073330) Show SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)oc12 Show InChI InChI=1S/C24H26N4O4/c29-22-5-4-21(20-3-6-23(30)32-24(20)22)27-14-12-26(13-15-27)10-1-2-16-31-19-8-11-28-18(17-19)7-9-25-28/h3-9,11,17,29H,1-2,10,12-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Erlangen-Nuernberg Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D4R expressed in CHO cell membranes by radioligand binding assay				J Med Chem 60: 4693-4713 (2017) Article DOI: 10.1021/acs.jmedchem.7b00363 BindingDB Entry DOI: 10.7270/Q2QC05NH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50239414 (CHEMBL4073330) Show SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)oc12 Show InChI InChI=1S/C24H26N4O4/c29-22-5-4-21(20-3-6-23(30)32-24(20)22)27-14-12-26(13-15-27)10-1-2-16-31-19-8-11-28-18(17-19)7-9-25-28/h3-9,11,17,29H,1-2,10,12-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Erlangen-Nuernberg Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2AR expressed in HEK293T cell membranes by radioligand binding assay				J Med Chem 60: 4693-4713 (2017) Article DOI: 10.1021/acs.jmedchem.7b00363 BindingDB Entry DOI: 10.7270/Q2QC05NH
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50239414 (CHEMBL4073330) Show SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)oc12 Show InChI InChI=1S/C24H26N4O4/c29-22-5-4-21(20-3-6-23(30)32-24(20)22)27-14-12-26(13-15-27)10-1-2-16-31-19-8-11-28-18(17-19)7-9-25-28/h3-9,11,17,29H,1-2,10,12-16H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Erlangen-Nuernberg Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human D5R expressed in HEK293T cell membranes by radioligand binding assay				J Med Chem 60: 4693-4713 (2017) Article DOI: 10.1021/acs.jmedchem.7b00363 BindingDB Entry DOI: 10.7270/Q2QC05NH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50239414 (CHEMBL4073330) Show SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2ccc(=O)oc12 Show InChI InChI=1S/C24H26N4O4/c29-22-5-4-21(20-3-6-23(30)32-24(20)22)27-14-12-26(13-15-27)10-1-2-16-31-19-8-11-28-18(17-19)7-9-25-28/h3-9,11,17,29H,1-2,10,12-16H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Erlangen-Nuernberg Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human D1R expressed in HEK293T cell membranes by radioligand binding assay				J Med Chem 60: 4693-4713 (2017) Article DOI: 10.1021/acs.jmedchem.7b00363 BindingDB Entry DOI: 10.7270/Q2QC05NH
					More data for this Ligand-Target Pair