Found 4 hits for monomerid = 50260040 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human)) | BDBM50260040
(CHEMBL4083149)Show SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C1CCCCC1)c1cncnc1 Show InChI InChI=1S/C33H42N6O/c1-24-20-39(31-18-34-23-35-19-31)22-29-16-27(8-9-32(24)29)33(40)36-30-15-25(21-38-12-10-37(2)11-13-38)14-28(17-30)26-6-4-3-5-7-26/h8-9,14-19,23-24,26H,3-7,10-13,20-22H2,1-2H3,(H,36,40) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human GST-tagged DDR1 catalytic domain expressed in baculovirus expression system using Fluorescein-Poly GAT as substrate m... |
ACS Med Chem Lett 8: 327-332 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00497
BindingDB Entry DOI: 10.7270/Q2N0190M |
More data for this
Ligand-Target Pair | |
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50260040
(CHEMBL4083149)Show SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C1CCCCC1)c1cncnc1 Show InChI InChI=1S/C33H42N6O/c1-24-20-39(31-18-34-23-35-19-31)22-29-16-27(8-9-32(24)29)33(40)36-30-15-25(21-38-12-10-37(2)11-13-38)14-28(17-30)26-6-4-3-5-7-26/h8-9,14-19,23-24,26H,3-7,10-13,20-22H2,1-2H3,(H,36,40) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full length His-tagged Bcr-Abl fusion protein cytoplasmic domain expressed in baculovirus expression system using tyr... |
ACS Med Chem Lett 8: 327-332 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00497
BindingDB Entry DOI: 10.7270/Q2N0190M |
More data for this
Ligand-Target Pair | |
Discoidin domain-containing receptor 2
(Homo sapiens (Human)) | BDBM50260040
(CHEMBL4083149)Show SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C1CCCCC1)c1cncnc1 Show InChI InChI=1S/C33H42N6O/c1-24-20-39(31-18-34-23-35-19-31)22-29-16-27(8-9-32(24)29)33(40)36-30-15-25(21-38-12-10-37(2)11-13-38)14-28(17-30)26-6-4-3-5-7-26/h8-9,14-19,23-24,26H,3-7,10-13,20-22H2,1-2H3,(H,36,40) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 462 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human GST-tagged DDR2 cytoplasmic domain expressed in baculovirus expression system using Fluorescein-Poly GAT as substrate... |
ACS Med Chem Lett 8: 327-332 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00497
BindingDB Entry DOI: 10.7270/Q2N0190M |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50260040
(CHEMBL4083149)Show SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C1CCCCC1)c1cncnc1 Show InChI InChI=1S/C33H42N6O/c1-24-20-39(31-18-34-23-35-19-31)22-29-16-27(8-9-32(24)29)33(40)36-30-15-25(21-38-12-10-37(2)11-13-38)14-28(17-30)26-6-4-3-5-7-26/h8-9,14-19,23-24,26H,3-7,10-13,20-22H2,1-2H3,(H,36,40) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His-tagged c-kit cytoplasmic domain (544 to 976 residues) expressed in baculovirus expression system using Ser/Thr 6 ... |
ACS Med Chem Lett 8: 327-332 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00497
BindingDB Entry DOI: 10.7270/Q2N0190M |
More data for this
Ligand-Target Pair | |
Search and Browse
