BDBM50261623 CHEMBL4095038

SMILES: COc1cc2CC3COC(=O)N3Cc2cc1OCc1ccccc1

InChI Key: InChIKey=ZEIDIAVJECYUTI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50261623 (CHEMBL4095038) Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OCc1ccccc1 Show InChI InChI=1S/C19H19NO4/c1-22-17-8-14-7-16-12-24-19(21)20(16)10-15(14)9-18(17)23-11-13-5-3-2-4-6-13/h2-6,8-9,16H,7,10-12H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri Curated by ChEMBL					Assay Description Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins				Bioorg Med Chem 25: 5709-5717 (2017) Article DOI: 10.1016/j.bmc.2017.08.045 BindingDB Entry DOI: 10.7270/Q2PG1V62
					More data for this Ligand-Target Pair