Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50261623'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50261623 (CHEMBL4095038) Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OCc1ccccc1 Show InChI InChI=1S/C19H19NO4/c1-22-17-8-14-7-16-12-24-19(21)20(16)10-15(14)9-18(17)23-11-13-5-3-2-4-6-13/h2-6,8-9,16H,7,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri Curated by ChEMBL					Assay Description Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins				Bioorg Med Chem 25: 5709-5717 (2017) Article DOI: 10.1016/j.bmc.2017.08.045 BindingDB Entry DOI: 10.7270/Q2PG1V62
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