BDBM50273189 3-[2-(4-Isopropyl-phenyl)-ethylsulfamoyl]-benzamidine::CHEMBL513433

SMILES: CC(C)c1ccc(CCNS(=O)(=O)c2cccc(c2)C(N)=N)cc1

InChI Key: InChIKey=HMBXCGWDHUVNKU-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50273189 (3-[2-(4-Isopropyl-phenyl)-ethylsulfamoyl]-benzamid...) Show SMILES CC(C)c1ccc(CCNS(=O)(=O)c2cccc(c2)C(N)=N)cc1 Show InChI InChI=1S/C18H23N3O2S/c1-13(2)15-8-6-14(7-9-15)10-11-21-24(22,23)17-5-3-4-16(12-17)18(19)20/h3-9,12-13,21H,10-11H2,1-2H3,(H3,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 10a by Dixon-plot method				Bioorg Med Chem Lett 18: 4682-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.009 BindingDB Entry DOI: 10.7270/Q208654H
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50273189 (3-[2-(4-Isopropyl-phenyl)-ethylsulfamoyl]-benzamid...) Show SMILES CC(C)c1ccc(CCNS(=O)(=O)c2cccc(c2)C(N)=N)cc1 Show InChI InChI=1S/C18H23N3O2S/c1-13(2)15-8-6-14(7-9-15)10-11-21-24(22,23)17-5-3-4-16(12-17)18(19)20/h3-9,12-13,21H,10-11H2,1-2H3,(H3,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human thrombin by Dixon-plot method				Bioorg Med Chem Lett 18: 4682-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.009 BindingDB Entry DOI: 10.7270/Q208654H
					More data for this Ligand-Target Pair