BDBM50275503 5-fluoro-1-(1'-(phenylsulfonyl)-1,4'-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::CHEMBL485755

SMILES: Fc1ccc2n(C3CCN(CC3)C3CCN(CC3)S(=O)(=O)c3ccccc3)c(=O)[nH]c2c1

InChI Key: InChIKey=YYFWUVQKYICWEJ-UHFFFAOYSA-N

Data: 1 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50275503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50275503 (5-fluoro-1-(1'-(phenylsulfonyl)-1,4'-bipiperidin-4...) Show SMILES Fc1ccc2n(C3CCN(CC3)C3CCN(CC3)S(=O)(=O)c3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C23H27FN4O3S/c24-17-6-7-22-21(16-17)25-23(29)28(22)19-8-12-26(13-9-19)18-10-14-27(15-11-18)32(30,31)20-4-2-1-3-5-20/h1-7,16,18-19H,8-15H2,(H,25,29)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M5 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5443-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.032 BindingDB Entry DOI: 10.7270/Q29K4B1C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50275503 (5-fluoro-1-(1'-(phenylsulfonyl)-1,4'-bipiperidin-4...) Show SMILES Fc1ccc2n(C3CCN(CC3)C3CCN(CC3)S(=O)(=O)c3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C23H27FN4O3S/c24-17-6-7-22-21(16-17)25-23(29)28(22)19-8-12-26(13-9-19)18-10-14-27(15-11-18)32(30,31)20-4-2-1-3-5-20/h1-7,16,18-19H,8-15H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at dopamine D2 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5443-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.032 BindingDB Entry DOI: 10.7270/Q29K4B1C
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50275503 (5-fluoro-1-(1'-(phenylsulfonyl)-1,4'-bipiperidin-4...) Show SMILES Fc1ccc2n(C3CCN(CC3)C3CCN(CC3)S(=O)(=O)c3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C23H27FN4O3S/c24-17-6-7-22-21(16-17)25-23(29)28(22)19-8-12-26(13-9-19)18-10-14-27(15-11-18)32(30,31)20-4-2-1-3-5-20/h1-7,16,18-19H,8-15H2,(H,25,29)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M1 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5443-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.032 BindingDB Entry DOI: 10.7270/Q29K4B1C
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50275503 (5-fluoro-1-(1'-(phenylsulfonyl)-1,4'-bipiperidin-4...) Show SMILES Fc1ccc2n(C3CCN(CC3)C3CCN(CC3)S(=O)(=O)c3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C23H27FN4O3S/c24-17-6-7-22-21(16-17)25-23(29)28(22)19-8-12-26(13-9-19)18-10-14-27(15-11-18)32(30,31)20-4-2-1-3-5-20/h1-7,16,18-19H,8-15H2,(H,25,29)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M3 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5443-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.032 BindingDB Entry DOI: 10.7270/Q29K4B1C
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50275503 (5-fluoro-1-(1'-(phenylsulfonyl)-1,4'-bipiperidin-4...) Show SMILES Fc1ccc2n(C3CCN(CC3)C3CCN(CC3)S(=O)(=O)c3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C23H27FN4O3S/c24-17-6-7-22-21(16-17)25-23(29)28(22)19-8-12-26(13-9-19)18-10-14-27(15-11-18)32(30,31)20-4-2-1-3-5-20/h1-7,16,18-19H,8-15H2,(H,25,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M4 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5443-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.032 BindingDB Entry DOI: 10.7270/Q29K4B1C
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50275503 (5-fluoro-1-(1'-(phenylsulfonyl)-1,4'-bipiperidin-4...) Show SMILES Fc1ccc2n(C3CCN(CC3)C3CCN(CC3)S(=O)(=O)c3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C23H27FN4O3S/c24-17-6-7-22-21(16-17)25-23(29)28(22)19-8-12-26(13-9-19)18-10-14-27(15-11-18)32(30,31)20-4-2-1-3-5-20/h1-7,16,18-19H,8-15H2,(H,25,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M2 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5443-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.032 BindingDB Entry DOI: 10.7270/Q29K4B1C
					More data for this Ligand-Target Pair