BDBM50292010 (Carboxymethyl-{[2-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-ethylcarbamoyl]-methyl}-amino)-acetic acid::CHEMBL35421

SMILES: NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CN(CC(O)=O)CC(O)=O)s1

InChI Key: InChIKey=TUIZMJVOYKYPOW-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50292010 ((Carboxymethyl-{[2-(5-sulfamoyl-[1,3,4]thiadiazol-...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CN(CC(O)=O)CC(O)=O)s1 Show InChI InChI=1S/C11H16N6O8S2/c12-27(24,25)11-16-15-10(26-11)14-6(18)1-2-13-7(19)3-17(4-8(20)21)5-9(22)23/h1-5H2,(H,13,19)(H,20,21)(H,22,23)(H2,12,24,25)(H,14,15,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase II				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50292010 ((Carboxymethyl-{[2-(5-sulfamoyl-[1,3,4]thiadiazol-...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CN(CC(O)=O)CC(O)=O)s1 Show InChI InChI=1S/C11H16N6O8S2/c12-27(24,25)11-16-15-10(26-11)14-6(18)1-2-13-7(19)3-17(4-8(20)21)5-9(22)23/h1-5H2,(H,13,19)(H,20,21)(H,22,23)(H2,12,24,25)(H,14,15,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against bovine carbonic anhydrase IV				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50292010 ((Carboxymethyl-{[2-(5-sulfamoyl-[1,3,4]thiadiazol-...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CN(CC(O)=O)CC(O)=O)s1 Show InChI InChI=1S/C11H16N6O8S2/c12-27(24,25)11-16-15-10(26-11)14-6(18)1-2-13-7(19)3-17(4-8(20)21)5-9(22)23/h1-5H2,(H,13,19)(H,20,21)(H,22,23)(H2,12,24,25)(H,14,15,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	268	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase I				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair