BDBM50292106 CHEMBL33648::[2-({[2-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-ethylcarbamoyl]-methyl}-amino)-ethylamino]-acetic acid

SMILES: NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CNCCNCC(O)=O)s1

InChI Key: InChIKey=REIGVLGTWNLCMV-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50292106 (CHEMBL33648 | [2-({[2-(5-Sulfamoyl-[1,3,4]thiadiaz...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CNCCNCC(O)=O)s1 Show InChI InChI=1S/C11H19N7O6S2/c12-26(23,24)11-18-17-10(25-11)16-7(19)1-2-15-8(20)5-13-3-4-14-6-9(21)22/h13-14H,1-6H2,(H,15,20)(H,21,22)(H2,12,23,24)(H,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase II				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50292106 (CHEMBL33648 | [2-({[2-(5-Sulfamoyl-[1,3,4]thiadiaz...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CNCCNCC(O)=O)s1 Show InChI InChI=1S/C11H19N7O6S2/c12-26(23,24)11-18-17-10(25-11)16-7(19)1-2-15-8(20)5-13-3-4-14-6-9(21)22/h13-14H,1-6H2,(H,15,20)(H,21,22)(H2,12,23,24)(H,16,17,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against bovine carbonic anhydrase IV				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50292106 (CHEMBL33648 | [2-({[2-(5-Sulfamoyl-[1,3,4]thiadiaz...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CNCCNCC(O)=O)s1 Show InChI InChI=1S/C11H19N7O6S2/c12-26(23,24)11-18-17-10(25-11)16-7(19)1-2-15-8(20)5-13-3-4-14-6-9(21)22/h13-14H,1-6H2,(H,15,20)(H,21,22)(H2,12,23,24)(H,16,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase I				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair