BDBM50292133 ({[2-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-ethylcarbamoyl]-methyl}-amino)-acetic acid::CHEMBL286108

SMILES: NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CNCC(O)=O)s1

InChI Key: InChIKey=DCIBBANBLKPKCU-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50292133 (({[2-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CNCC(O)=O)s1 Show InChI InChI=1S/C9H14N6O6S2/c10-23(20,21)9-15-14-8(22-9)13-5(16)1-2-12-6(17)3-11-4-7(18)19/h11H,1-4H2,(H,12,17)(H,18,19)(H2,10,20,21)(H,13,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase II				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50292133 (({[2-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CNCC(O)=O)s1 Show InChI InChI=1S/C9H14N6O6S2/c10-23(20,21)9-15-14-8(22-9)13-5(16)1-2-12-6(17)3-11-4-7(18)19/h11H,1-4H2,(H,12,17)(H,18,19)(H2,10,20,21)(H,13,14,16)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against bovine carbonic anhydrase IV				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50292133 (({[2-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)CNCC(O)=O)s1 Show InChI InChI=1S/C9H14N6O6S2/c10-23(20,21)9-15-14-8(22-9)13-5(16)1-2-12-6(17)3-11-4-7(18)19/h11H,1-4H2,(H,12,17)(H,18,19)(H2,10,20,21)(H,13,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase I				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair