BDBM50292151 CHEMBL32308::[(2-Hydroxy-phenyl)-(2-{(2-hydroxy-phenyl)-[2-(2-sulfamoyl-benzothiazol-6-yloxy)-ethoxycarbonylmethyl]-amino}-ethyl)-amino]-acetic acid

SMILES: NS(=O)(=O)c1nc2ccc(OCCOC(=O)CN(CCN(CC(O)=O)c3ccccc3O)c3ccccc3O)cc2s1

InChI Key: InChIKey=ILJNEBRGMAWPTI-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50292151 (CHEMBL32308 | [(2-Hydroxy-phenyl)-(2-{(2-hydroxy-p...) Show SMILES NS(=O)(=O)c1nc2ccc(OCCOC(=O)CN(CCN(CC(O)=O)c3ccccc3O)c3ccccc3O)cc2s1 Show InChI InChI=1S/C27H28N4O9S2/c28-42(37,38)27-29-19-10-9-18(15-24(19)41-27)39-13-14-40-26(36)17-31(21-6-2-4-8-23(21)33)12-11-30(16-25(34)35)20-5-1-3-7-22(20)32/h1-10,15,32-33H,11-14,16-17H2,(H,34,35)(H2,28,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase II				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50292151 (CHEMBL32308 | [(2-Hydroxy-phenyl)-(2-{(2-hydroxy-p...) Show SMILES NS(=O)(=O)c1nc2ccc(OCCOC(=O)CN(CCN(CC(O)=O)c3ccccc3O)c3ccccc3O)cc2s1 Show InChI InChI=1S/C27H28N4O9S2/c28-42(37,38)27-29-19-10-9-18(15-24(19)41-27)39-13-14-40-26(36)17-31(21-6-2-4-8-23(21)33)12-11-30(16-25(34)35)20-5-1-3-7-22(20)32/h1-10,15,32-33H,11-14,16-17H2,(H,34,35)(H2,28,37,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against bovine carbonic anhydrase IV				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50292151 (CHEMBL32308 | [(2-Hydroxy-phenyl)-(2-{(2-hydroxy-p...) Show SMILES NS(=O)(=O)c1nc2ccc(OCCOC(=O)CN(CCN(CC(O)=O)c3ccccc3O)c3ccccc3O)cc2s1 Show InChI InChI=1S/C27H28N4O9S2/c28-42(37,38)27-29-19-10-9-18(15-24(19)41-27)39-13-14-40-26(36)17-31(21-6-2-4-8-23(21)33)12-11-30(16-25(34)35)20-5-1-3-7-22(20)32/h1-10,15,32-33H,11-14,16-17H2,(H,34,35)(H2,28,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase I				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair